open access publication

Article, 2024

J-domain proteins: From molecular mechanisms to diseases

Cell Stress and Chaperones, ISSN 1355-8145, Volume 29, 1, Pages 21-33, 10.1016/j.cstres.2023.12.002

Contributors

Marszalek J. [1] De Los Rios P. [2] Cyr D. [3] Mayer M.P. [4] Adupa V. [5] Andreasson C. 0000-0001-8948-0685 [6] Blatch G.L. [7] [8] [9] Braun J.E.A. [10] Brodsky J.L. [11] Bukau B. 0000-0003-0521-7199 [4] Chapple J.P. [12] Conz C. [13] Dementin S. [14] Genevaux P. [15] Genest O. [14] Goloubinoff P. [16] Gestwicki J.E. [17] Hammond C.M. 0000-0003-0571-5710 [18] [19] Hines J.K. [20] Ishikawa K. [4] Joachimiak L.A. [21] Kirstein J. [22] Liberek K. [1] Mokranjac D. [23] Nillegoda N. [24] Ramos C.H.I. [25] Rebeaud M. [2] Ron D. [26] Rospert S. [13] Sahi C. [27] Shalgi R. [28] Tomiczek B. [1] Ushioda R. [29] Ustyantseva E. [30] Ye Y. [31] Zylicz M. Kampinga H.H. 0000-0002-8966-8466 (Corresponding author) [30]

Affiliations

  1. [1] Medical University of Gdansk
    2. [NORA names: Poland; Europe, EU; OECD];
  2. [2] Ecole Polytechnique Fédérale de Lausanne
    3. [NORA names: Switzerland; Europe, Non-EU; OECD];
  3. [3] University of North Carolina School of Medicine
    4. [NORA names: United States; America, North; OECD];
  4. [4] Ruprecht-Karls-Universität Heidelberg
    5. [NORA names: Germany; Europe, EU; OECD];
  5. [5] University of Groningen
    6. [NORA names: Netherlands; Europe, EU; OECD];

Abstract

J-domain proteins (JDPs) are the largest family of chaperones in most organisms, but much of how they function within the network of other chaperones and protein quality control machineries is still an enigma. Here, we report on the latest findings related to JDP functions presented at a dedicated JDP workshop in Gdansk, Poland. The report does not include all (details) of what was shared and discussed at the meeting, because some of these original data have not yet been accepted for publication elsewhere or represented still preliminary observations at the time.

Keywords

Evolution, Hsp70 cycle, JDP

Funders

  • University of Gdansk
  • Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk

Data Provider: Elsevier

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